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2 This result was demonstrated for the primary efficacy variable (change in pain intensity after 4 hours) and for multiple secondary efficacy variables, including pain relief, pain intensity reduction, response, sustained response, relief of associated symptoms, use of rescue medication, disability relief, and global assessments of effectiveness

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Barrier dysfunction in AD patients results from reduced expression of the filaggrin gene, ceramide deficiency and overexpression of epidermal proteases (1820)

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NOTE: When using this product around the eye area, use fingertips to carefully apply a thin layer (or 1-2 drops) underneath the eyes or on the outside areas of the eye